My wife (89, triple bypass in 2015, now diagnosed with Alzheimer's also) gets a dose of metoprolol each day so your article definitely perked up my ears. I trust her cardiologist to explore the best options for her. She is one of the few doctors who haven't decided that she's too old for regular health care.
I find disturbing that particular attitude of both politicians and their wealthy donors that old folks don't matter any more.
Have treated people for years. You are absolutely right regarding older people gets treated differently. Treatment should be based on their health and functionality. Goal is to optimize their health and functionality (ADLs). Some 90’s are healthier than some 70’s. CMS and health insurances denies part of the care by designating it due to old age. (eg hearing aides are not covered as this is part of aging. But can help and improve persons life and functions).
Dr. Mokotoff, this is a fantastic analysis and a masterclass in nuanced science communication. Thank you for deconstructing this complex new study with such clarity.
As a biochemist at The Ageless Engine, I was particularly impressed by your clear explanation of the beta-blocker paradox. You've perfectly articulated that the therapeutic benefit isn't mechanical, but hormonal - it's about shielding the already-stressed cardiac tissue from the chronically catabolic effects of excess adrenaline.
Your breakdown of the REBOOT study, especially the crucial nuance about ejection fractions and the specific subgroup of women, is a vital public service. It's a perfect example of why we must read beyond the headlines and engage with the primary data.
This is exactly the kind of clear, evidence-based thinking that is so desperately needed. Thank you for your work.
My wife (89, triple bypass in 2015, now diagnosed with Alzheimer's also) gets a dose of metoprolol each day so your article definitely perked up my ears. I trust her cardiologist to explore the best options for her. She is one of the few doctors who haven't decided that she's too old for regular health care.
I find disturbing that particular attitude of both politicians and their wealthy donors that old folks don't matter any more.
Have treated people for years. You are absolutely right regarding older people gets treated differently. Treatment should be based on their health and functionality. Goal is to optimize their health and functionality (ADLs). Some 90’s are healthier than some 70’s. CMS and health insurances denies part of the care by designating it due to old age. (eg hearing aides are not covered as this is part of aging. But can help and improve persons life and functions).
Very nicely and clearly explained the studies. Beta locker also causes erectile dysfunction in males which can cause anxiety and stress.
Thank you for your thoughtful analysis of the use of beta blockers in women.
Dr. Mokotoff, this is a fantastic analysis and a masterclass in nuanced science communication. Thank you for deconstructing this complex new study with such clarity.
As a biochemist at The Ageless Engine, I was particularly impressed by your clear explanation of the beta-blocker paradox. You've perfectly articulated that the therapeutic benefit isn't mechanical, but hormonal - it's about shielding the already-stressed cardiac tissue from the chronically catabolic effects of excess adrenaline.
Your breakdown of the REBOOT study, especially the crucial nuance about ejection fractions and the specific subgroup of women, is a vital public service. It's a perfect example of why we must read beyond the headlines and engage with the primary data.
This is exactly the kind of clear, evidence-based thinking that is so desperately needed. Thank you for your work.